Sodium concentration is normalized with the cancellation (dose reduction) deca durabolin cycleor conservative treatment (restriction of fluid intake). Patients with impaired renal function, and low concentration of sodium in the blood serum, or in patients receiving concomitant treatment with drugs that promote sodium excretion from the body (diuretics, drugs affecting the secretion of antidiuretic hormone) before therapy should determine the concentration of sodium in the serum. Further should be controlled in the serum sodium concentration of 2 weeks after initiation of therapy and then monthly for 3 months or as needed. With special attention to these risk factors should be treated in older patients. The appointment of diuretics and other drugs that reduce the concentration of sodium in the blood serum of patients treated should follow the same recommendations. When the appearance of clinical symptoms of hyponatremia, measure the sodium concentration in the blood serum. For the remaining patients, the measurement of the concentration of sodium in the blood serum can be carried out during routine blood tests.
In the treatment of patients in very rare cases, it noted the development of agranulocytosis, aplastic anemia and pancytopenia. Considering the small frequency of occurrence of agranulocytosis, aplastic anemia and pancytopenia, the presence of confounding factors (eg, concomitant use of other drugs, comorbidities), a causal relationship between the development of adverse events data and the use of the drug can not be established. With the development of symptom suppression of bone marrow hematopoiesis is necessary to consider the abolition of the drug.
Patients treated with anticonvulsants, rarely observed episodes of suicidal behavior and thinking. The results of meta-randomized placebo-controlled studies have shown a small increased risk of suicidal behavior in patients treated with anticonvulsants. The mechanism of increase suicide risk in these patients is not established. Stages of treatment requires careful monitoring of patients receiving drug treatment.
It is necessary to carry out the control of body weight in all patients with heart failure to timely identification of fluid retention. When liquid or delay in the progression of heart failure symptoms sodium concentration should be determined in the blood serum. In case of hyponatremia should limit the amount of fluid consumed. Since the use of oxcarbazepine in very rare cases may impair cardiac conduction, the need for careful monitoring of patients with prior conduction disturbances , receiving deca durabolin cycle. When using rarely reported on the development of severe dermatological reactions, such syndrome, toxic epidermal necrolysis (Lyell’s syndrome), exudative erythema multiforme. Patients with the above dermatological reactions may require hospitalization in connection with the development of life-threatening conditions; very rarely can be fatal. When applying dermatological reactions were observed in both children and adults, and developed an average of 19 days after the start of dosing. There are some reports of recurrence of skin reactions at the resumption of receiving . With the development of skin reactions during treatment should consider the abolition of the drug and the appointment of other antiepileptic drugs.
There have been reports of rare cases of hepatitis, which in most cases were resolved successfully. At suspicion on a hepatitis need to consider the abolition of the drug.
Women of childbearing age taking oral contraceptives at the same time should be warned about the possible decrease in the effectiveness of hormonal contraceptives. This category of patients receiving is recommended additional use non-hormonal methods of contraception.
Women of childbearing age recommended, if possible, as monotherapy.
As with any antiepileptic drugs, deca durabolin cycle should be withdrawn gradually because of the risk of increased frequency of seizures.
Trileptal in form for oral suspension contains ethanol in an amount of less than 100 mg per dose. The slurry also contains the parabens, which can cause allergic reactions (possibly delayed).
The structure of the suspension for oral administration include sorbitol, therefore Trileptal in the form of suspensions should not be administered to patients with the inherited disorder of tolerance to fructose.
The effect on the ability to drive vehicles and use machines Patients who during treatment with deca durabolin cyclearises dizziness, drowsiness or other disorders of the central nervous system, do not drive vehicles or operate machinery during treatment.